Obesity: A Chronic Disease and the Challenge of a Comprehensive Approach

 

by José Luis Cárdenas Tomažič
 
Adapted from the Spanish column originally published in El Economista on January 9th, 2026 (Obesidad: una enfermedad crónica y el desafío de un abordaje integral)
 

Obesity has ceased to be a purely aesthetic concern and has emerged as the greatest public health crisis of the 21st century. In every medical consultation, in every family, obesity is no longer a secondary issue—it has become a central concern.

At the beginning of 2026, figures confirm the worst projections: according to the World Obesity Atlas, more than 900 million adults are already living with obesity worldwide [1]. By 2030, it is expected that 3 billion people will be overweight or obese—an inflection point that threatens the sustainability of healthcare systems.

 

In fact, by 2035, the global cost associated with overweight and obesity could exceed USD 4.32 trillion annually (nearly 3% of global GDP), effectively undermining the sustainability of health systems [1].

Latin America: A Silent Epidemic

In our region, adult prevalence exceeds 60% in several countries, while childhood obesity is rising at alarming rates, compromising the future of new generations. This condition is driving an increasing number of cases of type 2 diabetes, hypertension, and at least 13 types of cancer at ever younger ages [2][3]. The economic impact is equally devastating: associated costs threaten to suffocate healthcare budgets.

Ending the Stigma: A Disease, Not a Choice

The scientific debate is settled: obesity is not a failure of willpower nor simply the result of “eating too much and moving too little.” This recognition not only transforms clinical practice but also compels health systems and society to rethink their policies and attitudes.

The WHO recognizes obesity as a chronic, complex, and multifactorial disease resulting from the interaction of genetic, neurobiological, behavioral, environmental, and social factors [4][5][6]. This paradigm shift is critical to:

  • Dismantling social stigma: addressing the neuroendocrine basis of the disease through a multidisciplinary team, ensuring that medical care focuses on the biological and hormonal mechanisms that regulate appetite, satiety, and energy expenditure, rather than placing sole responsibility on the patient’s habits.
  • Ensuring equitable access: incorporating pharmacological treatments and psychological support into public health systems.
From Dieting to Precision Pharmacology

In recent years, the therapeutic field has undergone a revolution. GLP-1 receptor agonists, such as semaglutide and tirzepatide, have achieved weight reductions of 15% to 22%—levels previously attainable only through bariatric surgery [7][8]. In addition, these drugs provide cardiorenal benefits, reducing the risk of heart attacks and strokes. However, access to these advances remains limited in many countries in the region, underscoring the need for public policies that ensure treatment equity.

Yet innovation is not a “magic solution”: it must be integrated into comprehensive care models that include behavioral changes and specialized medical support to ensure the sustainability of outcomes.

Public Policy: The Environment as Medicine

An individual-focused approach is insufficient if the environment remains obesogenic (referring to everything that promotes the development of obesity—environments or factors that encourage weight gain and hinder the adoption of healthy habits). Countries that have managed to stabilize their rates have implemented robust multisectoral strategies:

  • Strict regulation: front-of-package labeling and restrictions on advertising targeted at children.
  • Fiscal policies: taxes on sugar-sweetened beverages and subsidies for fresh foods.
  • Active urban planning: cities that promote non-motorized transport and access to green spaces [9][10].
The Challenge in 2026

We cannot treat a systemic disease with isolated solutions. A comprehensive approach requires:

  • Access to pharmacological innovations such as GLP-1 therapies, with proper clinical follow-up.
  • Transformational public policies that modify obesogenic environments.
  • A cultural shift that replaces judgment with empathy and prioritizes metabolic health.

Only coordinated action among governments, the private sector, healthcare professionals, and civil society will make it possible to reverse this trend and protect the health of future generations.